U.S. stocks mixed at close of trade; Dow Jones Industrial Average down 0.87%

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At the close in NYSE, the Dow Jones Industrial Average lost 0.87%, while the S&P 500 index added 0.16%, and the NASDAQ Composite index climbed 1.14%.

The best performers of the session on the Dow Jones Industrial Average were Apple Inc (NASDAQ:AAPL), which rose 2.37% or 2.87 points to trade at 123.86 at the close. Meanwhile, Microsoft Corporation (NASDAQ:MSFT) added 2.24% or 5.12 points to end at 234.11 and UnitedHealth Group Incorporated (NYSE:UNH) was up 1.61% or 5.29 points to 334.16 in late trade.

The worst performers of the session were Salesforce.com Inc (NYSE:CRM), which fell 5.37% or 12.40 points to trade at 218.68 at the close. Dow Inc (NYSE:DOW) declined 2.38% or 1.46 points to end at 59.89 and International Business Machines (NYSE:IBM) was down 2.38% or 2.92 points to 119.55.

The top performers on the S&P 500 were TripAdvisor Inc (NASDAQ:TRIP) which rose 12.65% to 49.05, Alliance Data Systems Corp (NYSE:ADS) which was up 5.70% to settle at 97.04 and L Brands Inc (NYSE:LB) which gained 5.06% to close at 55.01.

The worst performers were Foot Locker Inc (NYSE:FL) which was down 8.21% to 48.40 in late trade, EOG Resources Inc (NYSE:EOG) which lost 7.99% to settle at 64.95 and Universal Health Services Inc (NYSE:UHS) which was down 5.49% to 127.51 at the close.

The top performers on the NASDAQ Composite were Lixte Biotechnology Holdings Inc (NASDAQ:LIXT) which rose 50.66% to 5.68, Ocugen, Inc (NASDAQ:OCGN) which was up 33.62% to settle at 10.6900 and Intrusion Inc (NASDAQ:INTZ) which gained 31.81% to close at 24.74.

The worst performers were Recro Pharm (NASDAQ:REPH) which was down 31.06% to 3.38 in late trade, Tricida Inc (NASDAQ:TCDA) which lost 29.82% to settle at 5.17 and Guardion Health Sciences Inc (NASDAQ:GHSI) which was down 26.02% to 0.5140 at the close.

Falling stocks outnumbered advancing ones on the New York Stock Exchange by 1735 to 1365 and 70 ended unchanged; on the Nasdaq Stock Exchange, 1830 fell and 1360 advanced, while 66 ended unchanged.

Shares in Alliance Data Systems Corp (NYSE:ADS) rose to 52-week highs; gaining 5.70% or 5.23 to 97.04. Shares in L Brands Inc (NYSE:LB) rose to 3-years highs; up 5.06% or 2.65 to 55.01. Shares in Lixte Biotechnology Holdings Inc (NASDAQ:LIXT) rose to all time highs; up 50.66% or 1.91 to 5.68.

The CBOE Volatility Index, which measures the implied volatility of S&P 500 options, was down 6.85% to 26.91.

Gold Futures for April delivery was down 2.72% or 48.35 to $1727.05 a troy ounce. Elsewhere in commodities trading, Crude oil for delivery in April fell 3.04% or 1.93 to hit $61.60 a barrel, while the May Brent oil contract fell 2.51% or 1.66 to trade at $64.45 a barrel.

EUR/USD was down 0.83% to 1.2074, while USD/JPY rose 0.34% to 106.57.

The US Dollar Index Futures was up 0.87% at 90.918.